William
Wulftange.

MD-PHD CANDIDATEBIOMEDICAL ENGINEERING GURKAN LABGEN. SURGERY M3–M4

I build microfluidic devices that measure how living cells behave under force, and I’m training as a surgeon to put them to use.

MICROFLUIDICSCAR T MECHANODYNAMICSCRS / ICANS PREDICTIONBIOMEMSCELL THERAPY ANALYTICSSURGICAL ONCOLOGYDEVICE DEVELOPMENTMICROFLUIDICSCAR T MECHANODYNAMICSCRS / ICANS PREDICTIONBIOMEMSCELL THERAPY ANALYTICSSURGICAL ONCOLOGYDEVICE DEVELOPMENT

PUBLICATIONS15

H–INDEX10

CITATIONS700+

PATENTS FILED02

[ SEC.02 ]

Selected work

FIG. 01 — US20250099952A1

PORTED COVER PILLAR ARRAY GLASS BASE

DISSERTATION / GURKAN LAB × CLEVELAND CLINIC

Mechanodynamic profiling

A microfluidic panel measuring deformability, adhesion and capillary occlusion in clinical CAR T products, mapped onto patient outcomes. The signatures separate severe CRS and ICANS from uncomplicated courses.

STATUSMANUSCRIPT UNDER REVIEW

PATENTUS20250099952A1

MODALITYSHEAR / OCCLUSION / ADHESION

FIG. 02 — PROVISIONAL

INDEPENDENT / BENCH PROTOTYPE

Peroneal NMES device

A wearable stimulator that assists dorsiflexion during gait to cut trip risk in older adults. Sensing hardware, firmware, stimulation circuitry and enclosure built end to end.

STATUSPROVISIONAL FILED

TARGETCOMMON PERONEAL N.

STACKFIRMWARE / IMU / 3D PRINT

[ SEC.03 ]

Publications

001

Mechanodynamic profiling of CAR T-cells unveils predictors of clinical toxicities

Wulftange WJ, Jung S, Fadaei P, Meckovskyte F, et al.

UNDER REVIEW

002

Motion blur microscopy

Goreke U, Gonzales A, Shipley B, Wulftange WJ, et al.

NAT COMMUN / 2024

003

Real-time imaging of nanobubble contrast agent flow through an extracellular matrix

Cooley MB*, Wulftange WJ*, Wegierak D, et al.

LAB CHIP / 2023

004

A nanoporous two-dimensional polymer by single-crystal-to-single-crystal photopolymerization

Kissel P, Murray D, Wulftange WJ, Catalano VJ, King BT

NAT CHEM / 2014